Social determinants of tuberculosis via a zero-inflated model in small areas of a city in Southeastern Brazil
CONCLUSIONS: It is important to prioritize areas exhibiting determinants that influence the occurrence of TB in the municipality of Vitória. The zero-inflated model can be useful to the public health sector since it identifies the percentage of false zeros, genera ting an estimate of the real epidemiological condition of TB in Vitória.
Authors: Araujo-Mariz C, Militão de Albuquerque MFP, Lopes EP, Ximenes RAA, Lacerda HR, Miranda-Filho DB, Lustosa-Martins BB, Pastor AFP, Acioli-Santos B Abstract INTRODUCTION AND OBJECTIVE: Hepatotoxicity during tuberculosis (TB) treatment is frequent and may be related to the Arylamine N-Acetyltransferase (NAT2) acetylator profile, in which allele frequencies differ according to the population. The aim of this study was to investigate functional polymorphisms in NAT2 associated with the development of hepatotoxicity after initiating treatment for TB in people living with HIV/AIDS (PLWHA) in Pernambuco, Nor...
Conditions: Hiv; Tuberculosis Intervention: Drug: Dolutegravir Sponsors: Helen Reynolds; Infectious Disease Institute, Kampala, Uganda; Desmond Tutu HIV Centre Not yet recruiting