Molecular analysis, biofilm formation, and susceptibility of methicillin-resistant Staphylococcus aureus strains causing community- and health care-associated infections in central venous catheters

CONCLUSIONS: The superbug MRSA is a major cause of CVC-related infection. Antibiotic resistance to major classes of antibiotics and biofilm formation potential enhanced superbug MRSA virulence, leading to complicated infection. MRSA causes infection in hospitals, communities, and livestock.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research

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Functional finishes are agents that are applied to fabrics to make them suitable for specific uses and contribute a specific attribute to a fabric without altering its appearance. In this context, the present study reveals the importance of dyed fabrics with Datura stramonium plant leaf extracts to control antibiotic-resistant bacteria, which have been a threat to human health and posed noti...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research
AbstractMethicillin-resistantStaphylococcus aureus (MRSA) is an important cause of infections in humans. Photodynamic therapy using blue light (450  nm) could possibly be used to reduce MRSA on different human tissue surfaces without killing the human cells. It could be less harmful than 300–400 nm light or common disinfectants. We applied blue light ± riboflavin (RF) to MRSA and keratinocytes, in an in vitro liquid layer model, and compar ed the effect to elimination using common disinfection fluids. MRSA dilutions (8 × 105/mL) in wells were exposed to blue light (450  nm) &...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Conclusion: According to the results of the present study, Dracocephalum kotschyi can be a suitable compound for the synthesis of nanostructures due to its indigenous cultivation and great medicinal properties.
Source: Current Chemical Biology - Category: Biochemistry Source Type: research
Analyst, 2019, Advance Article DOI: 10.1039/C9AN02020A, PaperHui Yang, Xiao Zhao, Hui Wang, Wenfang Deng, Yueming Tan, Ming Ma, Qingji Xie Sensitive photoelectrochemical immunoassay ofStaphylococcus aureus is described using one-pot electrodeposited ZnS/CdS heterojunction nanoparticles as an optoelectronic material. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Raquel Ferrer-Espada1,2, Xiaojing Liu1,2, Xueping Sharon Goh1,2 and Tianhong Dai1,2* 1Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States 2Vaccine &Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States Polymicrobial biofilms, in which mixed microbial species are present, play a significant role in persistent infections. Furthermore, polymicrobial biofilms promote antibiotic resistance by allowing interspecies transfer of antibiotic resistance genes. In the present study, we investigated the effec...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CONCLUSIONDalbavancin may be an alternative option for DSWI caused by gram-positive bacteria when first line treatments are contraindicated or as a salvage treatment.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Publication date: Available online 27 October 2018Source: Inorganica Chimica ActaAuthor(s): Cillian O'Beirne, Nada F. Alhamad, Qinxi Ma, Helge Müller-Bunz, Kevin Kavanagh, Geraldine Butler, Xiangming Zhu, Matthias TackeAbstractThe rising threat of Antimicrobial Resistance (AMR) requires a novel approach to the treatment of infectious diseases. Covalently bonded silver, which has known antibacterial and antifungal properties and multiple mechanisms of action, may provide a treatment strategy when used alone or in combination with already known antimicrobial compounds. Here we describe the synthesis of eight novel silve...
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
Staphylococcus aureus is considered the most common causative agent of community and hospital-acquired infections. The isolates with increased virulence and antimicrobial resistance, especially mecithillin resistant S. aureus (MRSA), represent a challenge in hospitals and health care facilities worldwide. The effect of tyrosol, a phenolic quorum sensing compound of Candida albicans, was stud...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research
Discussion Antibiotic use was associated with an increased risk of colonization by Candida species alone and in conjunction with other multidrug-resistant organisms (MDROs). Antibiotic stewardship may be an important intervention for preventing colonization and subsequent infection by Candida and other MDROs.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Background: The epidemiology of paediatric bloodstream infection (BSI) in Sub-Saharan Africa is poorly documented with limited data on hospital-acquired sepsis, impact of HIV infection, BSI trends and antimicrobial resistance. Methods: We retrospectively reviewed paediatric BSI (0–14 years) at Tygerberg Children’s Hospital between 1 January 2008 and 31 December 2013 (excluding neonatal wards). Laboratory and hospital data were used to determine BSI rates, blood culture contamination, pathogen profile, patient demographics, antimicrobial resistance and factors associated with mortality. Fluconazole resistant Can...
Source: BMC Pediatrics - Category: Pediatrics Authors: Source Type: research
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