Histoplamosis in an immunocompetent man returning from Brazil: A diagnostic challenge helped by 18 FDG PET CT

A 43-year-old French man presented with fever, arthralgia, headache, night sweats and dry cough, 3 weeks after returning from Brazil. Physical examination was normal. He reported a visit at the botanic garden of Rio de Janeiro during a 7-day-trip. Blood tests revealed lymphocytosis (5.28G/L), C-reactive protein at 50mg/L, and cholestatic hepatitis (ASAT 148UI/L, ALAT 319UI/L, gamma-GT: 523UI/L, alkaline phosphatase: 234UI/L). Microbiological investigations were negative for the following: blood cultures, malaria quick test, Legionella pneumophila, Streptococcus pneumonia antigenuria; serology for HIV, Histoplasma, Brucella, Leptospira, blood PCR for C.

Source: Travel Medicine and Infectious Disease - October 6, 2018 Category: Infectious Diseases Authors: Cl émentine Montagnac, Carole Eldin, Anais Thouret, Stéphane Ranque, Philippe Brouqui Source Type: research