Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus.

This study provides the first genotype-phenotype observations as well as potential mechanistic clues associated with Wwox loss of function in the brain.
PMID: 30290271 [PubMed - as supplied by publisher]

Source: Neurobiology of Disease - October 2, 2018 Category: Neurology Authors: Hussain T, Kil H, Hattiangady B, Lee J, Kodali M, Shuai B, Attaluri S, Takata Y, Shen J, Abba M, Shetty AK, Marcelo Aldaz C Tags: Neurobiol Dis Source Type: research