The Gulf Familial Hypercholesterolemia Registry (Gulf FH): Design, Rationale and Preliminary Results.

CONCLUSIONS: The prevalence of FH in the adult population of the Arabian Gulf region is high. The Gulf FH registry, a first-of-a-kind multi-national study in the Middle East region, will help in improving underdiagnosis and undertreatment of FH in the region. PMID: 30289081 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research

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Precision metabolomics and quantification for cost-effective rapid diagnosis of disease are the key goals in personalized medicine and point-of-care testing. At present, patients are subjected to multiple test procedures requiring large laboratory equipment. Microelectronics has already made modern computing and communications possible by integration of complex functions within a single chip. As More than Moore technology increases in importance, integrated circuits for densely patterned sensor chips have grown in significance. Here, we present a versatile single complementary metal–oxide–semiconductor chip for...
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
BOSTON (CBS) — Marijuana use is growing in popularity and local doctors are sounding the alarm about the potential harms the drug could have on the heart. They say marijuana carries many of the same cardiovascular risks as smoking tobacco. Researchers at Brigham and Women’s Hospital say while more patients are curbing their use of cigarettes, there has been an acceleration in marijuana use that marijuana users are now exceeding cigarette smokers. And the effects of the drug on cardiovascular health are not fully understood. Some studies have linked marijuana use with stroke, arrhythmias, and other heart conditi...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated CBSN Boston Syndicated Local Dr. Mallika Marshall Marijuana Source Type: news
The J.P. Morgan Healthcare conference runs every year in San Francisco, a big draw for the biotech industry, and many organizations take the opportunity to host events at the same time. Among these, the SENS Research Foundation has for the past few years hosted a pitch day in which biotech companies in the longevity industry, largely startups, present to that portion of the Bay Area investor community interested in funding the treatment of aging as a medical condition. I was there to present on progress at Repair Biotechnologies, and took some notes on the other companies as they talked about their work. Kimera Labs ...
Source: Fight Aging! - Category: Research Authors: Tags: Investment Source Type: blogs
The high saturated fat content of coconut oil could be driving adverse cholesterol changes, authors of a new review of published studies suggest.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news
In this study, there was no increased risk of adverse outcomes (including muscle aches, liver dysfunction, new onset of diabetes, cancer, and bleeding strokes), even when LDL was lowered to as low as 20 mg/dL. Although statin medications themselves have been linked to side effects, especially at high doses, it appears that extremely low LDL concentrations are not responsible for side effects. In other words, lowering LDL beyond our previous target of 70 mg/dL appears to be not only safe but beneficial, in patients with CVD. The post LDL cholesterol: How low can you (safely) go? appeared first on Harvard Health Blog.
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Drugs and Supplements Health Heart Health Source Type: blogs
(Natural News) We’ve all had it drilled into our heads that high cholesterol is bad and bringing it down with statins can prevent a heart attack. However, that doesn’t explain why many people who take statins still end up developing cardiovascular disease. A recent study shows that there’s far more to the cardiovascular disease equation...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
AbstractA 10-week feeding experiment was carried out examining the effects of deoxynivalenol (DON)-contaminated maize treated with different sodium sulphite (SoS) concentrations on performance, health and DON-plasma concentrations in fattening pigs. Two maize batches were used: background-contaminated (CON, 0.73  mg/kg maize) andFusarium-toxin contaminated (DON, 44.45  mg/kg maize) maize. Both were wet preserved at 20% moisture content, with one of three (0.0, 2.5, 5.0 g/kg maize) sodium sulphite concentrations and propionic acid (15%). Each maize batch was then mixed into a barley-wheat-based diet at a proportio...
Source: Mycotoxin Research - Category: Toxicology Source Type: research
Study finds unequal dementia care Related items fromOnMedica Fund specialist dementia training to improve care and save money NHS care lets down 'far too many patients' Experts urge radical action on mental health crises CQC's State of Care report finds standards improving but warns of pressures Statins of small and uncertain benefit in primary prevention
Source: OnMedica Latest News - Category: UK Health Source Type: news
Lots of studies demonstrated that CD4+ T cells regulate the development of atherosclerosis (AS). Previously, we reported that LCK, a key molecule in activation of T cell receptor (TCR) signalling and T cells, adversely affects reverse cholesterol transport (RCT), which ameliorates AS in vitro. To investigate the effect of LCK on AS in vivo, we injected the LCK inhibitor, PP2, into ApoE −/− mice fed a chow diet or a high-fat diet (HFD). Although, AS plaques were not affected by PP2 in chow diet-fed mice, PP2 significantly reduced the lesion percentage and necrotic core areas in HFD-fed mice.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Source Type: research
ász Csanádi Vígh Bácskay BGP-15 is a new insulin sensitizer drug candidate, which was developed by Hungarian researchers. In recent years, numerous research groups have studied its beneficial effects. It is effective in the treatment of insulin resistance and it has protective effects in Duchenne muscular dystrophy, diastolic dysfunction, tachycardia, heart failure, and atrial fibrillation, and it can alleviate cardiotoxicity. BGP-15 exhibits chemoprotective properties in different cytostatic therapies, and has also proven to be photoprotective. It can additionally have advantageou...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
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