Individualized Treatment for Infantile Hemangioma

In this study, the authors chose individual treatment for different patients. From January 2012 to December 2016, 185 patients with hemangioma were enrolled into this study. Lesion area ranged from 0.5 cm × 0.5 cm to 9 cm × 12 cm. The initial treatment age ranged from 1 to 7 months with an average age of 3.9 months. Thirty-five children achieved the treatment of Intralesional Compound Betamethasone, 134 children achieved the treatment of oral propranolol, and 16 children achieved the treatment of topical carteolol. In the follow-up, the treatment could be repeated or switched to oral propranolol if the tumor tended to grow again. At the end of follow-up, 89% of the patients’ tumors shrinked or involuted completely, 5 patients switched to oral propranolol. The adverse effects included soft tissue atrophy, moon face, diarrhea, heart rate reduction, and liver enzyme abnormalities. All of the patients recovered in a short period. Early treatment for hemangioma can achieve good results and avoid functional impairment. For different patients, the authors suggest individualized treatment according to the tumors’ size and location.
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Clinical Studies Source Type: research

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We present a rare case of a neonate with PHACES syndrome (posterior fossa malformations, large facialhemangiomas, cerebralarterial anomalies,cardiovascular anomalies,eye anomalies andsternal clefting orsupraumbilical raphe) and diffuse hemangiomatosis of the ileum, presenting with multiple intestinal perforations and peritonitis. The infant was successfully treated with propranolol and methylprednisolone as well as octreotide, tranexamic acid, and supportive therapy for massive intestinal bleeding. 
Source: Acta Dermatovenerologica Croatica - Category: Dermatology Source Type: research
The authors report a rare case of intraosseous hemangioma of the mandible in a 14-year-old male. Surgical intervention with embolization is as important as histological and radiological examination to reduce the bleeding complication. Magnetic resonance angiography is paramount of importance in these lesions to detect the supplier arteries.
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Brief Clinical Studies Source Type: research
Endoscopy DOI: 10.1055/a-1073-7559 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text
Source: Endoscopy - Category: Gastroenterology Authors: Tags: E-Videos Source Type: research
Central hemangioma (CH) of the jaws is a rare benign vascular neoplasm of variable radiographic appearance. A 32-year-old man was referred for evaluation of an ulcerated mass on the anterior mandible causing facial asymmetry for the last 6 months. The patient reported progressive growth and bleeding episodes. Intraoral examination revealed an erythematous and necrotic swelling in the lower anterior gingiva. Computerized tomography revealed a well-defined multilocular hypodense lesion involving the mandibular symphysis, containing hyperdense foci, with expansion and destruction of the buccal cortical bone, and teeth displacement and mobility.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
Intramuscular hemangioma (IH) is relatively uncommon, accounting for less than 1% of all hemangiomas, usually located within the skeletal muscles of the trunk or limbs, particularly in the pelvic region. Approximately 10% of IH may occur in the head and neck region, most commonly affecting the masseter, sternocleidomastoid, and trapezius muscles. A 57-year-old man was referred for evaluation of a 4-cm asymptomatic, bluish, and slow-growing swelling of the lower lip. The patient's history included lower lip trauma and bleeding 5 years earlier.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
ConclusionsThe aim of this case report is to describe our surgical strategy to manage a giant vascular malformation of the tongue and improve quality of life through a median glossectomy with trapezoidal wedge resection of the tongue, as previously described for surgical management of macroglossia.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
The resection of distal airways obstructing tumours is a traditional indication of therapeutic bronchoscopy. Lung cancer is the most frequent cause of the obstruction. Takeout procedures of the benign tumours, endobronchial carcinoids and endobronchial metastases are considerably less frequent. These tumours can be removed completely, some of them definitively. Present work analyses experience with these tumours in one tertiary bronchological centre. During the period from 1993 to 2018, 29.121 bronchoscopies were performed and 124 benign tumours, 19 typical carcinoids (G1 NET) and 35 endobronchial metastases were removed. ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional pulmonology Source Type: research
In this study, we summarized the literature with regards to the effectiveness of topical beta blockers for the treatment of PG, and discussed all published case reports, case series, and open-label single arm trials. J Drugs Dermatol. 2019;18(10):1006-1010. PMID: 31584779 [PubMed - as supplied by publisher]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Intraosseous hemangioma (IH) in the maxillofacial area is a very uncommon neoplasm. Here, the authors show an exceptional case not previously reported in the literature of a 65-year-old man who presented with a pathological mandibular fracture following a facial trauma that was the first sign of an occult cavernous IH. Complete excision of the tumor in the mandibular ramus reduced the risk of severe bleeding and prevented long-term recurrence, whereas immobilization of the fracture obtained an excellent functional result. This clinical report highlights the possibility that a previously unknown primary IH may debut as a pa...
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Brief Clinical Studies Source Type: research
Publication date: September–October 2019Source: Reports of Practical Oncology &Radiotherapy, Volume 24, Issue 5Author(s): Dorota Księżniak-Baran, Sławomir Blamek, Agata Roch-Zniszczoł, Wojciech Osewski, Maja JędrzejewskaAbstractFifty-three-year-old male suffering from a presumptive non-functioning pituitary adenoma was qualified for stereotactic radiosurgery in our institution. Two attempts of surgical treatment were taken three months before radiotherapy. Excessive bleeding did not allow to remove the tumour or to take samples for histopathological examination. Diagnosis was put on the basis of radiological...
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
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