Decreased Behavioral Abnormalities After Treatment with Combined Donepezil and Yokukansankachimpihange in Alzheimer Disease: An Observational Study. The Osaki-Tajiri Project

ConclusionThese results suggest that combined treatment ofyokukansankachimpihange with donepezil has a positive clinical effect on improving the behavioral abnormalities, despite the lack of any effect on cognitive functions. Improvements in the diurnal rhythm may improve affective disturbance and anxiety. Thus,yokukansankachimpihange is considered to have a mild stabilizing effect on emotion.
Source: Neurology and Therapy - Category: Neurology Source Type: research

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