Genome-wide association analysis suggests novel loci for Hashimoto ’s thyroiditis

ConclusionsAlthough discovered loci are implicated with susceptibility to HT for the first time, genomic regions harboring these loci exhibit good biological candidacy due to involvement in the regulation of the thyroid function and autoimmunity. Additionally, we observe genetic overlap between HT and several related traits, such as hypothyroidism, Graves ’ disease and TPOAb. Our study adds a new knowledge of underlying HT genetics and sets a firm basis for further research.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research