Network analysis of drug effect on triglyceride-associated DNA methylation
ConclusionsThe same 3 modules, which were differentially methylated between pre- and posttreatment, were identified using both WGCNA module-preservation and GHD methods. Pathway analysis revealed that triglyceride-associated modules contain groups of genes that are involved in lipid signaling and metabolism. These 3 modules may provide insight into the effect of fenofibrate on changes in triglyceride levels and these methylation sites.
Source: BMC Proceedings - Category: Biomedical Science Source Type: research
More News: Biomedical Science | Cancer | Cancer & Oncology | Environmental Health | Fenofibrate | Genetics | Tricor