Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39)

Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01108G, PaperSang-Yong Lee, xihuan luo, Vigneshwaran Namasivayam, Jennifer Geiss, Salahuddin Mirza, Julie Pelletier, Holger Stephan, Jean Sevigny, Christa E Muller Ecto-nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39) is a major ectonucleotidase that hydrolyzes proinflammatory ATP via ADP to AMP, which is subsequently converted by ecto-5 ’-nucleotidase (CD73) to immunosuppressive adenosine. Activation of CD39... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Analyst latest articles - October 5, 2018 Category: Chemistry Authors: Sang-Yong Lee Source Type: research