Autosomal dominant PKD gets an atomic map

Autosomal dominant PKD gets an atomic mapAutosomal dominant PKD gets an atomic map, Published online: 02 October 2018; doi:10.1038/s41581-018-0066-7The polycystin complex structure has been solved at near-atomic resolution. Its surprising architecture provides new insights into the transient receptor potential (TRP) family of cation channels and the pathogenesis of autosomal dominant polycystic kidney disease. This discovery should have a transformative impact on the development of treatment strategies to cure the disease.

Source: Nature Reviews Nephrology - October 2, 2018 Category: Urology & Nephrology Authors: Paul A. Welling Source Type: research