Needs assessment: towards a more responsive Canadian Society of Nephrology Annual General Meeting (CSN AGM) program
ConclusionsTo our knowledge, this is the first published example of a needs assessment for a nephrology CME event that considers both the perceived and unperceived needs of the membership. The results of this exercise are currently being used to assist in the development of a more responsive CME program.
Purpose of review The current understanding of the incidence, predisposing factors, pathophysiology and effective treatment of recurrent glomerulonephritis (RGN) in renal transplants remains at best patchy and at worst, completely lacking. Current reports have been limited by inconsistencies in study design, sample populations and lengths of follow-up. Making sense of the available evidence will provide the tools to support transplant nephrologists in their management of allograft donors and recipients. Recent findings With better survival of renal allografts, RGN has become a dominant factor influencing allograft sur...
ConclusionTechnique failure in the first year of PD initiation occurs in one-fifth of PD patients and is associated with peripheral vascular disease and cause of end-stage kidney disease.
We report a case of a young female who presented as RPGN but diagnosis was revised to crescentic FGN after electron microscopy and immunohistochemical staining with DNAJB9 stain. Patient remained dialysis-dependent after treatment with steroid and cyclophosphamide for 2 months and progressed to end-stage renal disease (ESRD). Crescentic FGN usually does not respond to treatment and invariably progresses to ESRD over few months. This case emphasizes the defining role of electron microscopy and special stains in diagnosing uncommon glomerular diseases. PMID: 32657244 [PubMed - as supplied by publisher]
Conclusion: This study revealed that patients at the nephrology unit of KATH, Ghana, are mainly adults between ages 46-55. The clinical pattern of renal diseases is dominated by CKD and ESRD. We conclude that hypertension, chronic glomerulonephritis, diabetic nephropathy, and sepsis are the most common causes of renal diseases. The commonest clinical presentations are bilateral leg edema, palpitations, headache, breathlessness, dizziness, and vomiting. Early diagnosis and management of these conditions may prevent or delay the progress to end-stage renal disease. PMID: 32328308 [PubMed]
We report a 77 year old female with well-controlled hypertension who presented with lethargy. She had received antimicrobial treatment with ceftriaxone, levofloxacin and clarithromycin for acute sinusitis and pneumonia 2 weeks prior to presentation. Serum creatinine was 51 µmol/L then. At presentation, she had acute kidney injury with peak serum creatinine of 482 µmol/L and required dialysis. Urine analysis noted few iso-morphic red blood cells and white blood cells and proteinuria of 2.03 g/24 hours.
We report a 77-year-old woman with well-controlled hypertension who presented with lethargy. She had received antimicrobial treatment with ceftriaxone, levofloxacin, and clarithromycin for acute sinusitis and pneumonia 2 weeks prior to presentation. Serum creatinine was 51 µmol/L at that time. At presentation, she had acute kidney injury with peak serum creatinine of 482 µmol/L and required dialysis. Urine analysis noted few isomorphic red blood cells and white blood cells and proteinuria of 2.03 g/24 h.
Publication date: Available online 3 September 2019Source: American Journal of Kidney DiseasesAuthor(s): Chao Yang, Haibo Wang, Xinju Zhao, Kunihiro Matsushita, Josef Coresh, Luxia Zhang, Ming-Hui ZhaoDiabetes is the leading cause of kidney failure worldwide, whereas glomerulonephritis has been predominant in developing countries such as China. The prevalence of obesity and diabetes has increased dramatically in developing countries, substantially affecting the patterns of chronic kidney disease (CKD) observed in these regions. Using data from the Hospital Quality Monitoring System to evaluate changes in the spectrum of no...
Conclusion: Most common etiology of PRS is ANCA positive vasculitis in India. With high degree of suspicion for DAH in patients presenting with haemoptysis, breathlessness and alveolar opacities in chest x-ray and carefully investigating by simple urine examination for evidence of GN, timely diagnosis of PRS can be made. With timely appropriate treatment survival is 68%. Patients with PRS due to leptospirosis or dengue have features suggestive of underlying disease (like icterus with raised bilirubin but
Conclusion: Hemodialysis can affect various ocular parameters including SFCT, RAC and RVC, which changed significantly following hemodialysis. Whereas BCVA, IOP and CMT did not change after hemodialysis in ESRD patients. The systemic compensatory mechanisms of the changes in SBP, DBP, body weight following hemodialysis need further study. PMID: 31269848 [PubMed - in process]
Crescentic glomerulonephritis (GN) without immune reactants or deposits (referred to as pauci-immune) is typically characterized by the presence of anti-neutrophilic cytoplasmic antibodies (ANCA). While ANCA-negative patients might be expected to have a more benign course, they often have poor renal outcomes, especially without treatment with steroids and immune-modulating therapy. Pauci-immune crescentic GN can also co-exist with other autoimmune conditions, including rheumatoid arthritis (RA). Here, we describe an ANCA-negative patient with RA who developed dialysis-requiring acute kidney injury (AKI) with findings consi...