Remote Ischemic Conditioning (RIC) in a Rat Model of Testicular Torsion: Does it Offer Testicular Protection?

Testicular torsion is a surgical emergency mainly affecting adolescent boys, with a relatively high rate of missed torsion and testicular loss secondary to delay in prompt diagnosis and surgical intervention. With ischemic-reperfusion injury as its underlying culprit, testicular torsion may respond favorably to remote ischemic conditioning (RIC) where a non-privileged site (e.g. limb) is concurrently rendered ischemic to divert the cascade of reperfusion injury from the privileged organ (e.g. testicle), thus offering a protective effect in improving salvage.
Source: Journal of Pediatric Urology - Category: Urology & Nephrology Authors: Source Type: research