Prognostic value of microRNAs in head and neck cancers: a systematic review and meta-analysis protocol

DiscussionThere is a lack of highly sensitive and specific biomarkers for estimating the HNC patients ’ prognostic outcomes, particularly in post-treatment conditions. This systematic review will identify and validate specific miRNA as prognostic biomarkers by utilising a collection of previously published data on miRNA expression and survival. Highlighting these prognostic specific miRNAs will ha ve major clinical implications by allowing for better overall treatment strategies and patient survival estimates, by offering clinicians a method of quantitatively analysing prognosis via miRNA expression.Systematic review registrationThis review protocol was registered on PROSPERO and assigned the registration numberCRD42017077411.
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research