Relationship between endotoxin core, staphylococcal and varicella antibody levels and outcome following aortic valve replacement surgery: a prospective observational study

ConclusionsThis study again suggests the inverse relationship between endotoxin core antibody levels and outcome following aortic valve surgery as well as suggesting a similar relationship with antibodies to staphylococcus. There is no such relationship for antibody levels against an organism not providing a peri-operative threat. Understanding this relationship may enable therapeutic manipulation of immune status, re-evaluation of risk and further investigation of the low immune state.Trial registrationThe patients in this study are a sub-group of the RELIEF AS study.ClinicalTrials.gov identifierNCT02174471.
Source: Perioperative Medicine - Category: Surgery Source Type: research