New Drug Approved for Antibiotic-Resistant Lung Disease

Title: New Drug Approved for Antibiotic-Resistant Lung DiseaseCategory: Health NewsCreated: 10/1/2018 12:00:00 AMLast Editorial Review: 10/2/2018 12:00:00 AM
Source: MedicineNet Lungs General - Category: Respiratory Medicine Source Type: news

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In this study, we aimed to investigate the presence of PVL in S.aureus strains isolated from patients who had surgical site infections after orthopedic surgery, and also the clinical status of these patients. Between 2013 and 2017, 101 patients who had SSIs due to S.aureus after orthopedic surgery were included in the study. Identification of the strains was determined by conventional methods and "Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry" (MALDI-TOF MS). Methicillin resistance was determined by Kirby-Bauer disc diffusion method and automated system (Vitek 2, bioMérieux, ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Authors: Santovito E, das Neves J, Greco D, D'Ascanio V, Sarmento B, Logrieco AF, Avantaggiato G Abstract Rosin acids (RA) from coniferous trees are used in folk medicine for healing various skin infections. Despite the antimicrobial potential of RA, their poor solubility in aqueous media may limit their use. In this work RA-loaded polyethylene glycol-poly(lactic-co-glycolic acid) nanoparticles (RA-NPs) with enhanced antimicrobial properties against foodborne bacterial pathogens were produced. RA-NPs were prepared by solvent displacement technique and characterized for relevant colloidal features by dynamic light s...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
This study discusses the utilisation of Enterococcus lactis Q1 and 4CP3 strains to evaluate the antioxidant and the efficacy potential against the development of biofilms formed by methicillin-resistant Staphylococcus aureus (MRSA) strains. E. lactis Q1 and 4CP3 used alone and in combination showed an interesting antioxidant capacity using the in vitro 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+) free radical scavenging assays. The combination C6 (E. lactis Q1 at 40% and E. lactis 4CP3 at 60%) was the most active in the DPPH free radical scavenging test. Furth...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
(Natural News) The word “antibiotic” is a combination of the words “anti”, meaning “against”, and “biotic”, meaning “life”. It essentially means that antibiotics are “against life” as they are used to fight living bacteria that can cause harmful diseases. The problem is that when antibiotics are overused, this can result in antibiotic-resistant superbugs that can contribute...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
ConclusionThese findings show that pets and veterinarians could be potential sources of MDR-MRSA and MDR-MRSP in Iran. Taken together, these findings warrant future investigations on the epidemiology and public-health significance of MDR-MRSA and MDR-MRSP both in veterinarians and companion animals in Iran.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
This study was performed to evaluate the total phenols, flavonoids, and antioxidant activities of twenty-four propolis samples from different regions of Morocco. In addition, two samples were screened regarding the antibacterial effect against four Staphylococcus aureus strains. Gas chromatography coupled to mass spectra (GC-MS) analysis was done for propolis samples used in antibacterial tests. The minimum inhibitory and minimum bactericidal concentration (MIC, MBC) were determined. The potential to acquire the resistance after sequential exposure of bacterial strains and the impact of adaptation to propolis on virulence ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
(Natural News) Society is beginning to pay the price for years of antibiotic overuse, with superbugs claiming more and more lives every year and causing grave concern among health organizations and some medical professionals. Many are trying to reduce the number of antibiotic prescriptions they dole out, and one area where great reductions could potentially...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
uo Meng Yi Bi Antibiotic resistance has become a serious global problem that threatens public health. In our previous work, we found that ocotillol-type triterpenoid saponin showed good antibacterial activity. Based on preliminary structure-activity relationship, novel serious C-3 substituted ocotillol-type derivatives 7–26 were designed and synthesized. The in vitro antibacterial activity was tested on five bacterial strains (B. subtilis 168, S. aureus RN4220, E. coli DH5α, A. baum ATCC19606 and MRSA USA300) and compared with the tests on contrast. Among these derivatives, C-3 position free hydro...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: Available online 16 November 2018Source: Journal of Hospital InfectionAuthor(s): V. Pintado, R. Pazos, M.E. Jiménez-Mejías, A. Rodríguez-Guardado, B. Díaz-Pollán, C. Cabellos, J.M. García-Lechuz, J. Lora-Tamayo, P. Domingo, E. Muñez, D. Domingo, F. González-Romo, J.A. Lepe-Jiménez, C. Rodríguez-Lucas, A. Gil, I. Pelegrín, F. Chaves, V. Pomar, A. Ramos, T. AlarcónSummaryBackgroundStaphylococcus aureus meningitis is an uncommon nosocomial infection usually associated with neurosurgical procedures, but spontaneous infections ...
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
ConclusionThe decline in MRSA BSI rates, which was observed in our institution, was associated with changes in the population structure of the organism. This decline may be related to biologic properties of the prevailing MRSA clones.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
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