A cross sectional study in cognitive and neurobehavioral impairment in long-term nasopharyngeal cancer survivors treated with intensity-modulated radiotherapy

Neurocognitive dysfunction occurs among cancer survivors across a broad spectrum of solid non-CNS malignancies [1 –4], including head and neck cancers (HNC) [5–9]. Lee et al. presented the first series recognizing neurocognitive dysfunction following radiotherapy for nasopharyngeal carcinoma (NPC) in 1989, however, subsequently minimal progress has been made [10]. Most published series predate intensity-mod ulated radiotherapy (IMRT) and heavily focus on cohorts with and without temporal lobe necrosis (TLN) [7,10–18].

Source: Radiotherapy and Oncology - September 29, 2018 Category: Radiology Authors: Lachlan J. McDowell, Jolie Ringash, Wei Xu, Biu Chan, Lin Lu, John Waldron, Kathy Rock, Nathaniel So, Shao Hui Huang, Meredith Giuliani, Andrew Hope, Brian O'Sullivan, Scott V. Bratman, John Cho, John Kim, Raymond Jang, Andrew Bayley, Lori J. Bernstein Tags: Original article Source Type: research