High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults

Insulin resistance is a common feature of metabolic syndrome that may be influenced by genetic risk factors. We hypothesized that genetic risk scores (GRS) of SNPs that influence insulin resistance and signaling interact with lifestyles to modulate insulin resistance in Korean adults.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 28, 2018 Category: Nutrition Authors: James W. Daily, Meiling Liu, Sunmin Park Source Type: research