Properties of oscillatory neuronal activity in the basal ganglia and thalamus in patients with Parkinson ’s disease

ConclusionThe alterations in neuronal activity in basal ganglia play a critical role in generation of parkinsonism. β oscillatory activity is more prominent in basal ganglia than in thalamus suggesting that the activity likely results from dopaminergic depletion. While both basal ganglia and thalamus have tremor activity, the thalamus appears to play a more important role in tremor production, and basal ganglia β oscillatory activity might be the trigger.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research