Effective Reserve: A Latent Variable to Improve Outcome Prediction in Stroke
Prediction of functional outcome after stroke based on initial presentation remains an open challenge, suggesting that an important aspect is missing from these prediction models. There exists the notion of a protective mechanism called brain reserve, which may be utilized to understand variations in disease outcome. In this work, we expand the concept of brain reserve (effective reserve) to improve prediction models of functional outcome after acute ischemic stroke (AIS). Consecutive AIS patients with acute brain magnetic resonance imaging (
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Markus D. Schirmer, Mark R. Etherton, MD, PhD, Adrian V. Dalca, PhD, Anne-Katrin Giese, MD, Lisa Cloonan, MSc, Ona Wu, PhD, Polina Golland, PhD, Natalia S. Rost, MD, MPH, FAAN Source Type: research