Porphyria Cutanea Tarda Improvement With Elbasvir/Grazoprevir in End-Stage Renal Disease

A 56-year-old woman with chronic hepatitis C virus (HCV), cirrhosis, and end-stage renal disease (ESRD) was referred for evaluation. On examination, she had multiple painful vesicular lesions that progressed to crusting (Figure A). Laboratory results showed HCV genotype 1a with a viral load of 92,200 IU/mL. Plasma porphyrin levels were increased as follows: hexacarboxylporphyrin, 6.1 ug/L; heptacarboxylporphyrin, 41.5 ug/L; coproporphyrin, 1.8 ug/L; uroporphyrin, 129.2 ug/L; and total plasma porphyrin, 181.4 ug/L.

Source: Clinical Gastroenterology and Hepatology - August 9, 2018 Category: Gastroenterology Authors: Gurbir Sehmbey, Anil Seetharam Tags: Electronic Image of the Month Source Type: research