Endoscopic vs. microscopic transsphenoidal surgery for Cushing ’s disease: a systematic review and meta-analysis

ConclusionsEndoscopic surgery for patients with Cushing ’s disease reaches comparable results for microadenomas, and probably better results for macroadenomas than microscopic surgery. This is present despite the presumed learning curve of the newer endoscopic technique, although confounding cannot be excluded. Based on this study, endoscopic surgery m ay thus be considered the current standard of care. Microscopic surgery can be used based on neurosurgeon’s preference. Endocrinologists and neurosurgeons in pituitary centers performing the microscopic technique should at least consider referring Cushing’s disease patients with a macroadenoma.
Source: Pituitary - Category: Endocrinology Source Type: research