Dysfunction of the pancreas is related to a number of diseases, most famously diabetes. Conditions such as cystic fibrosis-related diabetes (CFRD), are particularly difficult to study in a laboratory setting, but researchers at Cincinnati Children&rs...
Source: Medgadget - Category: Medical Devices Authors: Medgadget EditorsTags: Materials Medicine Source Type: blogs
Conclusion: These results demonstrate the high prevalence of extrapulmonary comorbidities in transplanted CF adult patients particularly CFRD. We highlight the need for specific surveillance and prevention for transplanted CF patients who were already treated for extra espiratory comorbidities before lung transplantation, due to the potential aggravation of their comorbidities after transplantation.
PMID: 31267788 [PubMed - as supplied by publisher]
Protein folding is the process by which a polypeptide chain acquires its functional, native 3D structure. Protein misfolding, on the other hand, is a process in which proteins fails to fold into its native functional conformation. This misfolding of proteins may lead to precipitation of number of serious diseases such as Cystic fibrosis (CF), Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) etc. Protein quality-control (PQC) systems, consisting of molecular chaperones, proteases and regulatory factors, help in protein folding and prevent its aggregation. At the s...
Source: Current Protein and Peptide Science - Category: Biochemistry Authors: Yadav K, Yadav A, Priyanka, Pandey VP, Dwivedi UNTags: Curr Protein Pept Sci Source Type: research
ConclusionSex, CF ‐related diabetes, sinonasal infection status, allergic rhinitis, and nasal steroid use may all modulate severity of CF‐CRS in adults. Sinusitis exacerbation may be a precursor to pulmonary exacerbation.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Anna C. Zemke,
Seyed Mehdi Nouraie,
Jordan R. Gaston,
Nicholas R. Rowan,
Joseph M. Pilewski,
Jennifer M. Bomberger,
Stella E. LeeTags: ORIGINAL ARTICLE Source Type: research
PURPOSE: We seek to determine how youth with chronic medical conditions experience alcohol screening and counseling. METHODS: Adolescents with type I diabetes, juvenile idiopathic arthritis, moderate persistent asthma, cystic fibrosis, attention de...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: T. Meredith, V. Bright, A. Causer, S. Janis, M. Cummings, A. Shepherd, M. Allenby, I. Arregui-Fresneda, M. Carroll, T. Daniels, G. Connett, Z. SaynorTags: E-Poster Sessions Source Type: research