More Than 100 Elementary School Students Stung by Wasps in British Columbia
KAMLOOPS, British Columbia - Chaos at Dufferin Elementary School today as 135 students were stung by wasps during the annual Terry Fox Run. The incident occurred just before lunch on the hillside behind the school, says Principal Colleen Topolovec. The school called in some medical personnel to help out. Thankfully, she says none of the students appeared to suffer a life-threatening reaction. Read more at cfjctoday.com Editor's Take: Although this occured in Canada, something like this could easily happen in any of our communities. And with parents having trouble getting (or affording) Epi-pens, EMS and other first responders may need to carry extra. Bystander Epinephrine in Community Anaphylaxis Critical Updates in Assessment &Management of Anaphylaxis Treat Anaphylactic Incidents Before it’s Too Late
This article provides highlights of the original research published in 2018 issues of JACI: In Practice on the subjects of anaphylaxis, asthma, dermatitis, drug allergy, eosinophilic disorders, food allergy, immune deficiency, rhinitis/upper respiratory disease, and urticaria/angioedema. Within each topic, practical aspects of diagnosis and management are emphasized. Treatments discussed include lifestyle modifications, allergen avoidance therapy, positive and negative effects of pharmacologic therapy, and various forms of immunologic and desensitization management. We hope this review will help readers consolidate and use...
ConclusionsImmediate hypersensitivity to PEG 3350 with cross-reactive polysorbate 80 hypersensitivity may be under recognized in clinical practice and can be detected with clinical skin testing. Our studies raise the possibility of an IgE mediated Type I hypersensitivity mechanism in some cases.
Publication date: Available online 14 December 2018Source: The LancetAuthor(s): Kimberly G Blumenthal, Jonny G Peter, Jason A Trubiano, Elizabeth J PhillipsSummaryAntibiotics are the commonest cause of life-threatening immune-mediated drug reactions that are considered off-target, including anaphylaxis, and organ-specific and severe cutaneous adverse reactions. However, many antibiotic reactions documented as allergies were unknown or not remembered by the patient, cutaneous reactions unrelated to drug hypersensitivity, drug-infection interactions, or drug intolerances. Although such reactions pose negligible risk to patie...
Publication date: Available online 12 December 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Peter Capucilli, Katie Kennedy, Ashley M. Kazatsky, Antonella Cianferoni, Jonathan M. SpergelabstractClinical ImplicationsPectin is a structural heteropolysaccharide previously associated with occupational asthma and only rare accounts of allergy. Few case reports, however, suggest that pectin may contribute to atypical or idiopathic food reactions, particularly in patients with IgE-mediated allergy to tree nuts.
Conclusion: In our cohort of patients, ibuprofen hypersensitivity affected females more commonly than males, and presented with mainly cutaneous manifestations. Onset of symptoms was rapid (#x3c; 60 min). Reactions typically ranged in severity from mild to moderate although there was a risk of severe anaphylaxis. There was potential cross-reactivity with other NSAIDs or acetaminophen. The results of our study contribute to the understanding of the demographics and clinical course of ibuprofen hypersensitivity reactions.Int Arch Allergy Immunol
Promising new research offers hope to the many kids, teens, and adults who are peanut-allergic.Medscape Internal Medicine
CONCLUSIONS: The majority of calls were not consistent with anaphylaxis, and EMS dispatchers rarely strictly followed the Medical Priority Dispatch System guidelines aimed at identifying anaphylaxis. Future studies would be beneficial to determine if our findings hold true in other EMS service areas. PMID: 30526221 [PubMed - as supplied by publisher]
Because house dust mites (HDMs) are found in the environment, they are mostly considered as a source of allergens involved in respiratory allergies. The works from Sanchez-Borges et al1 and others have demonstrated that HDMs can contaminate food, which can trigger allergic reactions including severe manifestations such as grade 4 anaphylaxis on its ingestion.2-4 These acute reactions are observed in patients who are already sensitized to HDMs. Our work further highlights that the first step for the development of allergy toward HDMs, that is, allergic sensitization, can be induced by oral exposure to HDMs through breast milk.
CONCLUSIONS Our study found that adherence to SCIT is low in a real-life setting in southeast Turkey, similar to most previous adherence studies. PMID: 30537763 [PubMed - in process]
Publication date: February 2019Source: Respiratory Physiology &Neurobiology, Volume 260Author(s): Prafull Bandopant Ninave, Savita Dattatray PatilAbstractZizyphus jujuba Mill, a famous oriental traditional medicine, has been reported to exhibit diverse activities in biological systems including the respiratory system. However, a little information is available on its antiasthmatic activity. Jujuboside B (JB) is a natural saponin and one of the active constituent of fruits of Zizyphus jujuba. In the present investigation, JB was isolated from ethanolic extracts of fruits of Zizyphus jujuba (EZJF). EZJF and JB were then ...