Breast plasmacytoma with associated amyloidosis mimicking breast carcinoma

The Breast Journal, EarlyView.
Source: The Breast Journal - Category: Cancer & Oncology Authors: Source Type: research

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Publication date: Available online 17 September 2019Source: Pathology - Research and PracticeAuthor(s): Xiao-tong Wang, Ru Fang, Sheng-bing Ye, Ru-song Zhang, Rui Li, Xuan Wang, Rong-hao Ji, Zhen-feng Lu, Heng-hui Ma, Xiao-jun Zhou, Qiu-yuan Xia, Qiu RaoAbstractAnaplastic lymphoma kinase (ALK)-rearranged renal cell carcinoma (RCC) is a novel entity of rare tumors with only 10 cases reported in the literature. Three RCC cases bearing VCL-ALK gene fusion were all young African American patients and associated with sickle cell trait notably. In contrast to the 3 reported cases, this neoplasm occurred in a middle-age woman (57...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 17 September 2019Source: SteroidsAuthor(s): Anjali Verma, Nofrat Schwartz, D. Joshua Cohen, Barbara D. Boyan, Zvi SchwartzAbstractLaryngeal squamous cell carcinoma (LSCC) has been shown to respond to 17β-estradiol. However, the presence and characterization of estrogen receptors (ER) and other sex hormone receptors in LSCC are still being determined. Sex hormone receptors and the way sex hormones impact LSCC tumors are important for understanding which patients would benefit from hormone therapies, such as anti-estrogen therapies. This information also has prognostic value, as there ...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 22 June 2019Source: Biomedicine &PharmacotherapyAuthor(s): Erica Mie Akagi, Paulo Luiz de Sá Júnior, Simone Michaela Simons, Maria Helena Bellini, Sandra Alves Barreto, Ana Marisa Chudzinski-Tavassi
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 18 June 2019Source: Biomedicine &PharmacotherapyAuthor(s): Jinghao Qin, Hongbing Shi, Yanjie Xu, Fang Zhao, Qing Wang
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
ConclusionRosA can inhibit the proliferation and invasion of hepatocellular carcinoma cell in vitro and inhibit tumour growth in vivo and the mechanism may relate to inhibiting the activation of PI3K/AKT signal pathway.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
This study aims to design and synthesize Endostatin (ENT)-loaded nanoparticles using Folic acid (FA) as a driver for targeted anti-proliferative chemotherapy in Esophageal Squamous Cell Carcinoma (ESCC). An ionic gelation method was employed to formulate FA-decorated, ENT-loaded nanoparticles, which were tested in vitro on KYSE-30 cells using unbiased stereological approaches. FA-ENT nanoparticles were internalized into ESCC cells with preferential binging to the nucleus and mitochondria for necrotic and apoptotic effects. Nanoparticles showed increased proliferation inhibition of 64.71% and reduced KYSE-30 cell migration ...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
ConclusionsHigh CEL expression may be an independent prognostic factor for the poor survival of breast cancer.
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research
Authors: Ahmed SR, Petersen E, Patel R, Migden MR Abstract INTRODUCTION: In September of 2018, the United States Federal Drug Administration (FDA) approved cemiplimab-rwlc (Libtayo) for advanced cutaneous squamous cell carcinoma (CSCC). Cemiplimab is an intravenous human monoclonal antibody directed against programmed cell death-1 receptor (PD-1). Cemiplimab blocks T-cell inactivation and enhances the immune system's anti-tumor response. Areas Covered: We review CSCC and the studies leading to cemiplimab's approval, including common side effects and safety issues experienced during the clinical trials. Expert Opini...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Publication date: Available online 17 September 2019Source: Genes &DiseasesAuthor(s): Prasanna.K. Santhekadur, Divya.P. KumarAbstractRNA-induced silencing complex (RISC) is one of the basic eukaryotic cellular machinery which plays a pivotal role in post-transcriptional gene regulation. Discovery of miRNAs and their role in gene regulation have changed the course of modern biology. The method of gene silencing using small interfering RNAs and miRNAs has become major tool in molecular biology and genetic engineering. Hepatocellular carcinoma (HCC) is a very common malignancy of liver in developing countries and due to v...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
We present a 66 year-old-man that was referred to our center after the casual finding of a renal mass. With a suspected diagnosis of a renal cell carcinoma, a partial nephrectomy was performed. The histological study revealed the final diagnosis of a benign renal schwannoma.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
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