Radiofrequency Ablation of the Stellate Ganglion for Management of Acute Digital Ischemia: A Case Report

The authors present a report of a pulsed radiofrequency ablation of the stellate ganglion performed on a patient with microemboli to the hand from a thrombosed abandoned arteriovenous fistula. The patient was initially managed using vasodilators and anticoagulation. However, the patient’s skin mottling, pain, and decreased strength persisted. Ablation of the stellate ganglia increased perfusion to his hand and likely prevented amputation that has lasted for approximately 1 year. While radiofrequency ablation is more commonly used for pain syndromes, this is an example of its use in the treatment and potential treatment of acute ischemia.
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research

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ConclusionsThese results show that DRGS is equally effective when applied at low ‐, mid‐, and high‐frequency in an animal model of PDPN. However, low‐frequency‐(1 Hz)‐DRGS resulted in a delayed wash‐out effect, which suggests that this is the most optimal frequency for pain therapy in PDPN as compared to mid‐ and high‐frequency.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Basic Research Source Type: research
I have a patient with several months of coccyx pain. Worse with sitting, TTP over coccyx. Otherwise normal exam. No trauma, but she has an anteriorly displaced coccyx. Failed NSAIDs and no one around me does good pelvic floor PT. I scheduled her for ganglion impar injection, but her insurance won't pay for it. They wouldn't even let me to a peer-to-peer... they just straight up said they won't cover it. Any other treatment options? I don't want to send her to a surgeon. Thanks.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Abstract Prostaglandin E2 (PGE2) and proton are typical inflammatory mediators. They play a major role in pain processing and hypersensitivity through activating their cognate receptors expressed in terminals of nociceptive sensory neurons. However, it remains unclear whether there is an interaction between PGE2 receptors and proton-activated acid-sensing ion channels (ASICs). Herein, we show that PGE2 enhanced the functional activity of ASICs in rat dorsal root ganglion (DRG) neurons through EP1 and EP4 receptors. In the present study, PGE2 concentration-dependently increased ASIC currents in DRG neurons. It shif...
Source: Brain Research - Category: Neurology Authors: Tags: Brain Res Source Type: research
Publication date: Available online 6 September 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): G. Baranidharan, Ibrahim MohamedAbstractNeuropathic pain is a well-recognized chronic pain condition. This can have a significant impact in patients' quality of life. Neuromodulation is defined by the International Neuromodulation Society as ‘the therapeutic alteration of activity in the central or peripheral nervous system either electrically or pharmacologically’. Electrical stimulation can be performed at the motor cortex, deep brain, spinal cord, dorsal root ganglion, peripheral nerve and peripheral...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Complex regional pain syndrome (CRPS) type I and CRPS type II diminish quality of life and can lead to significant disability.15 Both conditions have varied and complex clinical features, with chronic debilitating pain being the primary symptom, usually involving the lower or upper extremities.16,24 The conditions are differentiated by the absence (CRPS-I) or presence (CRPS-II) of demonstrable nerve damage as an underlying etiology.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
This study evaluated the effect of bilateral endoscopic sphenopalatine ganglion block (SPGB) for management of postoperative pain in patients undergoing septoplasty.MethodsSixty septoplasty patients (51.7% male, 48.3% female, aged 18 to 45 years) were randomly assigned to general anesthesia (GA) alone (control) (n = 30) or GA plus endoscopic SPGB (n = 30). Demographic data, duration of surgery, blood loss, postoperative visual analogue scale (VAS) pain scores (upon arrival at the postanesthesia care unit [PACU] and 2, 6, 12, and 24 hours after surgery), overall analgesic usage (end of 24 and 168 hours after surgery), overa...
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
In this study, the biological effects and mechanisms of RACK1 contributes to the pathogenesis of chronic constriction injury (CCI)-induced neuropathic pain were investigated. By western blot and staining, we found that RACK1 protein changed in dorsal root ganglion (DRG) neurons and spinal cord (SC) neurons except glial cells after CCI. Especially, RACK1 was co-located with IB4-, CGRP-positive neurons, suggesting it was related to integrate nociceptive information from the primary afferents in DRG. The successful establishment of CCI models also directly led to mechanical allodynia and heat hyperalgesia, which could be rev...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
AbstractWe performed a study of the safety and efficacy of percutaneous pulsed radiofrequency (PRF) treatment directed at C1 and C2 levels as performed at our local pain clinic in refractory chronic cluster headache (CCH) patients. We identified 21 CCH patients treated with PRF (240  s, max. 45 V, max. 42 °C) directed at the ganglion and/or nerve root of C1 and C2. Data were collected through retrospective analysis of patients’ files and include demographic variables, onset and duration of the headache, mean attack frequency, and prior pharmacological treatment. Safety an d reduction of attack freq...
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research
ConclusionThis analysis of S1 DRG programming demonstrates that ideal positioning of the majority of the contacts for the electrode should be posterior and along the sacral border on fluoroscopic imaging. These findings also suggest that the S1 DRG may be located most reproducibly at the border of the intraforaminal and intracanalicular region.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
In the abstract “(206) Differential Transcriptome Analysis of Acutely Dissected and Cultured Human and Mouse Dorsal Root Ganglion,” published in the April 2019 issue (The Journal of Pain 2018;20:S26-S27), the first author's name was spelled incorrectly as A. Wangshou. The author's name should be A. Wangzhou.
Source: The Journal of Pain - Category: Materials Science Tags: Erratum Source Type: research
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