Insights into Human Hypertension and Renal Physiology from Human Genetics and Genomics

Date: Monday, 10 29, 2018; Speaker: Dr. Richard Lifton, MD, PhD, President of Rockefeller University ; Masur Auditorium, Building 10; Videocast Event
Source: NIH Calendar of Events - Category: American Health Source Type: events

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Publication date: Available online 17 September 2019Source: Journal of Cardiology CasesAuthor(s): Roberto Mijangos-Vázquez, Rogelio Hernández-Reyes, José R. López-JiménezAbstractGerbode defect is defined as an abnormal left ventricle–right atrium shunting which may have congenital or acquired origin, first described by Thurman in 1838, representing 0.08% of intracardiac shunts and
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
In this study, we investigated whether parental hypertension induces autonomic dysfunction in male adult offspring, and the H2S mechanism underlying this autonomic dysfunction. 2-kidney-1-clip method was employed to induce parental hypertension during pregnancy and lactation in rats. Basal blood pressure (BP) and autonomic function of male offspring in adulthood was evaluated. Additionally, either maternal hypertensive dams or their male offspring after weaning were treated with H2S to determine improving effects of H2S on autonomic dysfunction. The BP was significantly increased in male offspring of renovascular hypertens...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
(Reuters Health) - People living in communities with rising crime rates may be more likely than those in safer neighborhoods to develop high blood pressure, a new study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
In this study we assessed the diagnostic usefulness of transorbital sonography in IIH with a special focus on color Doppler imaging of the central retinal artery. IIH patients presented papilledema and enlarged ONSD. ONSD accurately predicted an increased intracranial pressure in IIH (cut-off: 5.8 mm, 81% sensitivity, 80% specificity). 24 h following therapeutic lumbar puncture ONSD diminished significantly, whereas papilledema was not changed. PSV (peak systolic velocity) and Vmean (mean flow velocity) of the central retinal artery were increased in IIH patients compared to controls. PSV accurately predicted an increa...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Authors: Johnston MP, Patel J, Byrne CD Abstract Introduction The pandemic of obesity over the last two decades has triggered a rise in prevalence of non-alcoholic fatty liver disease (NAFLD). NAFLD is associated with liver-related- and cardiovascular complications. Despite this, the first licensed drug for NAFLD is yet to be approved. Given the scale of the problem and unmet needs, there is a myriad of agents in the development pipeline. Areas covered We discuss promising agents in early phase clinical trials and categorize these agents based on their action on steatosis, steatohepatitis and fibrosis. Furthermore,...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
Experts from Mayo Clinic discuss practical patient management strategies in line with the 2017 ACC/AHA hypertension guideline.Mayo Clinic
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology Commentary Source Type: news
Conditions:   Hypertension;   Obesity Intervention:   Other: Observational study Sponsor:   Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Artery Hypertension;   Chronic Hepatitis c Intervention:   Diagnostic Test: transthoracic doppler-echocardiography (TTE) Sponsor:   Kantonsspital Olten Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Body Weight;   Obesity;   Overweight and Obesity;   Obesity, Abdominal;   Hypertension;   Hyperlipidemias;   Cardiovascular Diseases;   Coronary Heart Disease;   Stroke;   Mortality;   Dyslipidemias;   Diabetes;   PreDiabetes;   Insulin Tolerance;   Dysglycemia;   Metaboli c Syndrome Intervention:   Other: Nordic diet Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR);   Canada Research Chai...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
WEDNESDAY, Sept. 18, 2019 -- Four modifiable risk factors -- body mass index (BMI), the Dietary Approaches to Stop Hypertension (DASH) diet, alcohol use, and diuretic use -- could individually account for a notable proportion of hyperuricemia and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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