Neutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway disease

ConclusionsThe elucidation of molecular mechanisms driving neutrophil plasticity in vivo will open new treatment opportunities designed to modulate, rather than block, the crucial adaptive functions fulfilled by neutrophils. This review aims to outline emerging mechanisms of neutrophil plasticity and their participation in the building of pathological microenvironments in the context of cystic fibrosis and other diseases with similar features.
Source: Molecular and Cellular Pediatrics - Category: Cytology Source Type: research