Meta-analyses of the neural mechanisms and predictors of response to psychotherapy in depression and anxiety

Publication date: Available online 29 September 2018Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Lindsey Marwood, Toby Wise, Adam M. Perkins, Anthony J. CleareAbstractUnderstanding the neural mechanisms underlying psychological therapy could aid understanding of recovery processes and help target treatments. The dual-process model hypothesises that psychological therapy is associated with increased emotional-regulation in prefrontal brain regions and decreased implicit emotional-reactivity in limbic regions; however, research has yielded inconsistent findings. Meta-analyses of brain activity changes accompanying psychological therapy (22 studies, n = 352) and neural predictors of symptomatic improvement (11 studies, n = 293) in depression and anxiety were conducted using seed-based d mapping. Both resting-state and task-based studies were included, and analysed together and separately. The most robust findings were significant decreases in anterior cingulate/paracingulate gyrus, inferior frontal gyrus and insula activation after therapy. Cuneus activation was predictive of subsequent symptom change. The results are in agreement with neural models of improved emotional-reactivity following therapy as evidenced by decreased activity within the anterior cingulate and insula. We propose compensatory as well as corrective neural mechanisms of action underlie therapeutic efficacy, and suggest the dual-process model may be too simplistic to a...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research

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DiscussionThere is increasing demand for well-controlled studies on psychotherapeutic interventions in the postpartum period that do not only focus on particular risk groups. This randomized controlled trial (RCT) represents one of the first studies to investigate the efficacy of PIP in inpatient psychiatric departments and outpatient care centers in Germany. The results will fill knowledge gaps on the factors contributing to symptom reduction in postpartum mental disorders and improvements in mother-child relationships and help in developing preventive and therapeutic strategies for the fragmented German health care syste...
Source: Trials - Category: Research Source Type: clinical trials
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Mental Health and Wellness Podcast Psychology The Psych Central Show Source Type: blogs
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Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
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Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
Authors: Messiaen M, Duba A, Boulangeat C, Boucekine M, Bourbon A, Viprey M, Auquier P, Lançon C, Boyer L, Fond G Abstract Despite clues indicating high Bullying at the Work Place (BWP) rates in French hospitals, there has been no quantitative study so far. To determine the prevalence of repeated BWP in a national sample of French young physicians; its risk factors, and the mental health consequences of BWP. The study is a cross-sectional observational epidemiological national study addressed to young physicians. The online internet anonymous questionnaire was elaborated according to previous studies explori...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction Depression General Interview Podcast Policy and Advocacy Recovery Substance Abuse The Psych Central Show Source Type: blogs
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Source: Neurotherapeutics - Category: Neurology Source Type: research
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Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
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Source: Psychiatric Quarterly - Category: Psychiatry Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic General Green and Environment Interview LifeHelper Mental Health and Wellness Podcast Stress The Psych Central Show Source Type: blogs
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