SDF-1/CXCR4 axis promotes the growth and sphere formation of hypoxic breast cancer SP cells by c-Jun/ABCG2 pathway.

In conclusion, CXCR4 increases the growth and SFE of breast cancer SP cells under hypoxia through c-Jun-mediated transcriptional activation of ABCG2. PMID: 30274780 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30274780?dopt=Abstract

Source: Biochemical and Biophysical Research communications - September 28, 2018 Category: Biochemistry Authors: He C, Zhang H, Wang B, He J, Ge G Tags: Biochem Biophys Res Commun Source Type: research