Microbial diversity in infections of patients with medication-related osteonecrosis of the jaw.

CONCLUSION: The bacteria from the submucosal areas and the bottom of the infected bone presented comparable susceptibility to the common antibiotics regimes. Streptococcus spp., Prevotella spp., and Veillonella spp. present a high abundance in MRONJ lesions beside Actinomyces spp. The MRONJ lesions bottom is in many cases not infected by Actinomyces spp.
CLINICAL RELEVANCE: The removal of the necrotic bone reduces the variety of bacteria found in MRONJ lesions, in particular at the bottom of the lesion.
PMID: 30276516 [PubMed - as supplied by publisher]

Source: Clinical Prostate Cancer - October 1, 2018 Category: Cancer & Oncology Authors: Zirk M, Wenzel C, Buller J, Zöller JE, Zinser M, Peters F Tags: Clin Oral Investig Source Type: research