Successful management of heat stroke associated with multiple-organ dysfunction by active intravascular cooling

We report successful cooling with initial intravascular cooling use that rapidly achieved the target temperature with continued normothermia thereafter.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Case Report Source Type: research

Related Links:

Authors: PMID: 32463635 [PubMed - as supplied by publisher]
Source: American Family Physician - Category: Primary Care Tags: Am Fam Physician Source Type: research
AbstractPurpose of ReviewEffective thermoregulation is paramount for optimizing athletic performance and minimizing the risk of heat illness when exercising, especially in hot conditions. Para-athletes can face unique challenges in regard to thermoregulation and hydration, especially when travel is involved.Recent FindingsFor example, athletes with spinal cord injuries (SCI) have an impaired ability to thermoregulate due to a decreased sweat rate and ability to dissipate heat, thus making vigorous activity in the heat a challenge. These factors may put the athlete at risk for the following: dehydration, overheating, heat e...
Source: Current Nutrition Reports - Category: Nutrition Source Type: research
Conclusion: This study provides strong evidence that HS causes damage to both the small intestine and intestinal epithelial cells, scavenging ROS production can significantly alleviate such RIPK1/RIPK3-dependent necroptosis, mediating HS-induced intestinal damage both in vitro and in vivo. These findings provide a clear target for future mechanism-based therapeutic strategies for patients diagnosed with heat stroke. PMID: 32423248 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Publication date: Available online 18 May 2020Source: Journal of Science and Medicine in SportAuthor(s): Caroline Bosson, John Rendu, Laurent Pelletier, Amandine Abriat, Amandine Chatagnon, Julie Brocard, Jacques Brocard, Dominique Figarella-Branger, Sylvie Ducreux, Fabien van Coppenolle, Emmanuel Sagui, Isabelle Marty, Nathalie Roux-Buisson, Julien Faure
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Source Type: research
Heat stroke (HS) is the most acute type of heat illness accompanied with serious central nervous system (CNS) dysfunction. Despite the pathological process being clearly studied, effective treatment is deficient. Currently, mesenchymal stem cells (MSCs) have been demonstrated to have neuroprotective effects as there are no old ones. Thus, the purpose of the present study was to explore the neuroprotective effects and mechanisms of MSCs against HS-induced CNS injury. HS in rat models was induced by a high-temperature environment and treated with MSCs via the tail vein. The results demonstrated that MSC injection significant...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
CONCLUSIONS: Heat stroke-induced coagulopathy may be a driving mechanistic force in heat stroke pathology, especially when exacerbated by prior infection. Coagulation markers may serve as accessible biomarkers for heat stroke severity and therapeutic strategies. PMID: 32367690 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Tags: J Thromb Haemost Source Type: research
Publication date: July 2020Source: Biomedicine &Pharmacotherapy, Volume 127Author(s): Xiaojing Lin, Cheng-Hsien Lin, Ruoxu Liu, Chenyi Li, Shuxin Jiao, Xueqing Yi, M.J. Walker, Xiao-Ming Xu, Tingbao Zhao, Po-Chang Huang, Gang Sun
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Abstract BACKGROUND: Heat stroke-induced mortality is rising across the globe. So, the design of prophylactic and/or therapeutic modalities for heat stroke is pressing need. The common plant derived flavonoid exhibits strong anti-oxidant and anti-inflammatory activities; however, its effects in heat stroke remain unknown. The study aimed to investigate the cardioprotective effects of myricetin on heat stroke induced acute myocardial injury as well as lethality in rats and to explore the underlying mechanisms. METHODS: Myocardial injury was induced by subjecting the anesthetized rats to a high ambient temperat...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
To evaluate the prognostic value of routine coagulation tests for patients with heat stroke.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
Heat stroke is a serious medical condition that can cause multiple organ dysfunction, including central nervous system damage. The complications of heat stroke occur because of hypoperfusion, an inflammatory response, and thrombosis, resulting in variable ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Environmental Issues, Climate, Geophysics Source Type: news
More News: Emergency Medicine | Heatstroke | Stroke