Patients with diabetes are ‘up to 31 per cent more at risk of cancer’

Researches from Sweden and Manchester warned that diabetics are at a higher risk of developing cancer, and once they do they have far worse survival chance. For men the risk increases by 22%.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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3D sonographic measurement of papillary thyroid cancer nodules may be a better method of determining tumor size.Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
In this study, scientists screened cells from old animals to identify any RBPs that change upon aging. The screening showed that one particular protein, Pumilio2 (PUM2), was highly induced in old animals. PUM2 binds mRNA molecules containing specific recognition sites. Upon its binding, PUM2 represses the translation of the target mRNAs into proteins. Using a systems genetics approach, the researchers then identified a new mRNA target that PUM2 binds. The mRNA encodes for a protein called Mitochondrial Fission Factor (MFF), and is a pivotal regulator of mitochondrial fission - a process by which mitochondria break u...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
We present a unifying perspective on how the field is evolving and the need for an early amalgamation of engineering principles and a biological understanding of underlying phenomena in order to develop a therapy that is translatable to the clinic in a shorter time. PMID: 30651226 [PubMed - in process]
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
Publication date: Available online 17 January 2019Source: European Journal of Surgical OncologyAuthor(s): Elbert J. Mets, Fouad K. Chouairi, Kyle S. Gabrick, Tomer Avraham, Michael AlperovichAbstractBackgroundRacial disparities among patients who receive breast mastectomy and reconstruction have not been well characterized.MethodsRecords of patients undergoing breast extirpative and reconstructive surgery at a high-volume university-affiliated hospital over 5 consecutive years were reviewed. Patient demographics, breast cancer profiles, reconstructive modality, and outcomes were compared by race.ResultsA total of 1045 pati...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
We describe the epidemiologic shifts of CRC incidence and mortality across age groups as well as the differences in clinicopathologic, molecular, treatment, and survival characteristics between young and older patients. Novel studies of the microbiome may elucidate bacterial causes of CRC carcinogenesis in younger individuals. Moving up the colonoscopy screening to age 45 in normal-risk individuals should prove beneficial in detecting more patients with early-onset CRC.SummaryWe favor the development of risk-adaptive screening decision algorithms and flexible sigmoidoscopy screening at age 40 given the predilection for lef...
Source: Current Oncology Reports - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: Contemporary MHT does not seem to increase the risk of biliary tract cancer. The decreased risk of gallbladder cancer may be explained by the increased use of surgery for symptomatic gallstones in MHT users. PMID: 30656997 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Diabetes is one of the most frequent diseases throughout the world and its incidence is predicted to exponentially progress in the future. This metabolic disorder is associated with major complications such as neuropathy, retinopathy, atherosclerosis, and diabetic nephropathy, the severity of which correlates with hyperglycemia, suggesting that they are triggered by high glucose condition. Reducing sugars and reactive carbonyl species (RCS) such as methylglyoxal (MGO) lead to glycation of proteins, lipids and DNA and the gradual accumulation of advanced glycation end products (AGEs) in cells and tissues.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Tags: Invited review Source Type: research
Americans are obsessed with protein. It’s touted as the cornerstone of any healthy diet, since it helps people feel full and builds muscle. But most Americans eat too much protein every day, according to federal estimates—and they’re going especially overboard with animal proteins, namely red meat. It’s becoming clear how big a problem excessive red-meat consumption can be for health. Research has found associations between diets heavy in red and processed meats and many chronic diseases, including Type 2 diabetes, heart disease and cancer. Red meat comes with high amounts of saturated fat, and proc...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition Source Type: news
A celebrity feud has ignited debate over the popular — but somewhat controversial — ketogenic diet. It all started last week, when trainer Jillian Michaels told Women’s Health that the high-fat, low-carb keto diet is “a bad plan, for a million reasons.” “I don’t understand. Like, why would anybody think this is a good idea?” Michaels asked. It quickly became clear that many people, famous and otherwise, think the trendy plan is a good idea. Celebrities including Al Roker and Andy Cohen criticized Michaels’ take, causing her to double down on her position and offer to de...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition healthytime onetime Source Type: news
(Natural News) Recent estimates show that there are more than 80 million Americans who suffer from insulin resistance. This is a great cause for concern since in just a few years this can condition can progress to cardiovascular disease, high blood pressure, cancer, and diabetes. Insulin is an important metabolic hormone that triggers the uptake...
Source: - Category: Consumer Health News Source Type: news
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