GSE114237 Matrix mineralization controls gene expression in osteoblasts

Contributors : Oxana Schmidt ; Johannes Wischmann ; R üdiger von Eisenhart-Rothe ; Philipp Mayer-Kuckuk ; Günther H Richter ; Günther RichterSeries Type : Expression profiling by arrayOrganism : Homo sapiensOsteoblasts are adherent cells. Under physiological conditions they attach to mineralized and non-mineralized osseous surfaces. However, how exactly osteoblasts respond to these different osseous surfaces is largely unknown. Our hypothesis was that the state of matrix mineralization provides a functional signal to osteoblasts. To assess the osteoblast response to mineralized compared to demineralized osseous surfaces, we assessed the transcriptom.

Source: GEO: Gene Expression Omnibus - September 30, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research