Cerebral blood flow in striatal regions is associated with apathy in patients with schizophrenia.

CONCLUSION: The main finding of this study was a specific association between increased striatal rCBF and the negative symptom dimension of apathy. Our results further support the separate assessment of apathy and diminished expression when investigating the neural basis of negative symptoms. The ASL technique can provide a direct and quantitative approach to investigating the role of rCBF changes in the pathophysiology of negative symptoms. PMID: 30246686 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research