Isodose surface volumes in cervix cancer brachytherapy: Change of practice from standard (Point A) to individualized image guided adaptive (EMBRACE I) brachytherapy.

CONCLUSIONS: MR-IGABT and individualized dose prescription during EMBRACE I resulted in improved target dose coverage and decreased ISVs compared to standard plans used with classical Point A based brachytherapy. The ISVs depended strongly on CTVHR volume which demonstrates that dose adaptation was performed per individual tumour size and response during EBRT.
PMID: 30243671 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 19, 2018 Category: Radiology Authors: Serban M, Kirisits C, Pötter R, de Leeuw A, Nkiwane K, Dumas I, Nesvacil N, Swamidas J, Hudej R, Lowe G, Hellebust TP, Menon G, Oinam A, Bownes P, Oosterveld B, De Brabandere M, Koedooder K, Marthinsen ABL, Lindegaard J, Tanderup K, EMBRACE Collaborative Tags: Radiother Oncol Source Type: research