Effects of Risperidone and Paliperidone on Brain-Derived Neurotrophic Factor and N400 in First-Episode Schizophrenia.

Conclusions: Both risperidone and paliperidone could increase the serum BDNF levels in patients with first-episode schizophrenia and improve their cognitive function (N400 latency and amplitude), but their antipsychotic mechanisms might differ.
PMID: 30246715 [PubMed - in process]

Source: Chinese Medical Journal - September 25, 2018 Category: General Medicine Authors: Wu RQ, Lin CG, Zhang W, Lin XD, Chen XS, Chen C, Zhang LJ, Huang ZY, Chen GD, Xu DL, Lin ZG, Zhang MD Tags: Chin Med J (Engl) Source Type: research