TRKA expression and NTRK1 gene copy number across solid tumours.

CONCLUSIONS: TRKA expression can be found in 1.6% of solid tumours and can be paralleled by NTRK1 gene rearrangements or mostly GCN gain. The prognostic and translational therapeutic impact of the latter remains to be established. PMID: 29802225 [PubMed - indexed for MEDLINE]

https://www.ncbi.nlm.nih.gov/pubmed/29802225?dopt=Abstract

Source: Clinical Lung Cancer - September 23, 2018 Category: Cancer & Oncology Authors: Mauri G, Valtorta E, Cerea G, Amatu A, Schirru M, Marrapese G, Fiorillo V, Recchimuzzo P, Cavenago IS, Bonazzina EF, Motta V, Lauricella C, Veronese S, Tosi F, Maiolani M, Rospo G, Truini M, Bonoldi E, Christiansen J, Potts SJ, Siena S, Sartore-Bianchi A Tags: J Clin Pathol Source Type: research