Pathological interactions between mutant thyroid hormone receptors and corepressors and their modulation by a thyroid hormone analogue with therapeutic potential.
CONCLUSION: This study helps identify the specific interaction surfaces involved in the pathologic phenotype of TR mutants and TRIAC as a possible therapeutic agent for patients suffering from RTH syndromes.
PMID: 30235988 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
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