GSE120337 Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells

Contributors : Xuefei Wang ; Jilong ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensLncRNA-IIRX plays critical role in Bcr-Abl-induced tumorigenesis. To discover its mechanisms underlying cellular transformation by Bcr-Abl oncogene, genome-wide mRNA expression was measured by RNA-seq in K562 cells expressing shRNA targeting lncRNA-IIRX and control cells. We identified many genes with differential expression in K562 cells after knocking down lncRNA-IIRX.

Source: GEO: Gene Expression Omnibus - September 23, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research