Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

Publication date: October 2018Source: Phytochemistry Letters, Volume 27Author(s): Ritesh Raju, Ahilya Singh, Paul Reddell, Gerald MünchAbstractAnti-inflammatory activity guided isolation from Citrus garrawayi (Rutaceae) led to the discovery of five new garracoumarins A – E (1 - 5), and five known (6 – 10) isoprenylated furanocoumarins and the known sterol bourjotinolone A (11). Discussed herein is the anti-inflammatory structure activity relationship of the ten furanocoumarins and a detailed spectroscopic analysis leading to the structure elucidation of the new and known isoprenylated furanocoumarins.Graphical abstract

Source: Phytochemistry Letters - September 22, 2018 Category: Chemistry Source Type: research