New biphenyls from Garcinia lancilimba

Publication date: October 2018Source: Phytochemistry Letters, Volume 27Author(s): Xue-Mei Gao, Di Cui, Shan-Shan Wang, Wen-Zhong Huang, Gan-Peng Li, Guang-Zhi Zeng, Meng-Yuan Jiang, Zhi-Yong JiangAbstractGarcilancibiphenyls A–C (1–3), three new biphenyls, were isolated from the stems of the plant Garcinia lancilimba, which belongs to the family Clusiaceae. Structures of the new compounds feature the acetoxyprenyl group on a benzene ring, and were elucidated by spectroscopic evidence. These compounds showed promising anti-rotavirus activity effects with TI values above 10.Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research

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In this study we have characterized the whole genomes of five RVA strains (PAK56, PAK419, PAK585, PAK622, and PAK663) using the Illumina HiSeq platform. The strains PAK56 and PAK622 exhibited a typical Wa-like genotype constellation (G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1 and G3-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1, respectively), whereas PAK419, PAK585, and PAK663 exhibited distinct DS-1-like genotype constellations (G3P[4]-I2-R2-C2-M2-A2-N2-T1-E2-H2, G1P[8]-I2-R2-C2-M2-A2-N2-T2-E2-H2, and G3P[4]-I2-R2-C2-M2-A2-N2-T2-E2-H2, respectively). Despite their DS-1-like genotype constellation, strain PAK585 possessed the typical Wa-like G...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
AbstractWe modeled Group A Rotavirus (RVA) and Norovirus genogroup II (GII NoV) transport experiments in standardized (crystal quartz sand and deionized water with adjusted pH and ionic strength) and natural soil matrix-water systems (MWS). On the one hand, in the standardized MWS, Rotavirus and Norovirus showed very similar breakthrough curves (BTCs), showing a removal rate of 2 and 1.7 log10, respectively. From the numerical modeling of the experiment, transport parameters of the same order of magnitude were obtained for both viruses. On the other hand, in the natural MWS, the two viruses show very different BTCs. The No...
Source: Food and Environmental Virology - Category: Virology Source Type: research
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Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
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Source: Public Health Nutrition - Category: International Medicine & Public Health Authors: Tags: Public Health Nutr Source Type: research
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Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
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Source: Food and Environmental Virology - Category: Virology Source Type: research
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Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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