Vagino-rectal colonisation and maternal-neonatal transmission of Enterobacteriaceae producing extended-spectrum beta-lactamases or carbapenemases: a cross-sectional study

Publication date: Available online 22 September 2018Source: Journal of Hospital InfectionAuthor(s): Carlos Jiménez-Rámila, Lorena López-Cerero, Ma Valle Aguilar Martín, Consuelo Vera Martín, Lara Serrano, Álvaro Pascual, Jesús Rodríguez-Baño.AbstractWe studied the prevalence and risk factors for colonization with ESBL-and carbapenemase-producing Enterobacteriaceae (ESBL-E, CPE) in 815 mothers and 800 newborns using a cross-sectional design; 59 women and 13 neonates were colonized by ESBL-E (prevalence [95% confidence interval], 6.7% [5.2-8.7] and 1.6 [0.7-2.5], respectively). No CPE were found. The most frequent ESBLs were CTX-M-14 and SHV-12. Vertical transmission occurred in 14% of colonized mothers. The risk factors for colonization were: in mothers, complications in previous pregnancies,>1 urinary tract infection, non-caucasian ethnicity, and frequently having the mean meal outside home; in newborns, colonized mother and vaginal delivery.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research