Is psychedelic drug therapy on track to become as ubiquitous as meditation?

Psychedelic drugs show promise as a treatment for severe mental illnesses and addiction, but some believe the drugs could also benefit people without a mental health diagnosis.
Source: CBC | Health - Category: Consumer Health News Tags: Radio/Day 6 Source Type: news

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Publication date: Available online 16 March 2019Source: Neuroscience LettersAuthor(s): Brady J. Phelps, Tyler M. Miller, Heath Arens, Tayler Hutchinson, Kaitlyn A. Lang, Linda M. Muckey, Nicholas Thompson, Steven Stanage, Shafiqur Rahman, Scott M. RawlsAbstractWhile the psychoactive stimulant nicotine has been the subject of extensive research, considerably less attention has focused on other compounds found in either tobacco smoke or that are nicotine metabolites. Recent papers have suggested that some of the compounds in question may either alter nicotine’s effects or have reinforcing properties themselves, althoug...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 16 March 2019Source: PeptidesAuthor(s): Lori N. Eidson, Anne Z. MurphyAbstractEach year, over 50 million Americans suffer from persistent pain, including debilitating headaches, joint pain, and severe back pain. Although morphine is amongst the most effective analgesics available for the management of severe pain, prolonged morphine treatment results in decreased analgesic efficacy (i.e., tolerance). Despite significant headway in the field, the mechanisms underlying the development of morphine tolerance are not well understood. The midbrain ventrolateral periaqueductal gray (vlPAG) is a ...
Source: Peptides - Category: Biochemistry Source Type: research
Authors: Pergolizzi JV, Lequang JA, Passik S, Coluzzi F Abstract Healthcare professionals and organizations increasingly face the conundrum of treating patients with active substance use disorder, a history of personal or familial substance use disorder, or those at elevated risk for substance abuse. Such patients need compassionate care when facing painful conditions; in fact, denying them pain control makes it likely that they will seek out ways to self- medicate with illicit drugs. Yet it remains unclear how to safely and effectively treat patients in these challenging situations. The authors have formulated ten...
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
My colleagues and I in the tobacco control movement have based our entire careers on the principle that it is wrong to lie to the public. The bulk of our campaign against Big Tobacco was based on the contention that the cigarette companies lied to the public about the health risks of smoking. Numerous lawsuits were filed against Big Tobacco, seeking damages based on the claim that the companies are responsible because they misrepresented the health effects of their products, thus preventing smokers from making an informed choice. The name of the major youth anti-tobacco campaign is called " Truth. " Clearly, hone...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - Category: Addiction Source Type: blogs
In this study, the effects of low-dose METH administration prior to high-dose METH administration on movement and neural activity in rats were examined. Rats were administered low-dose (1 mg/kg/day) METH or saline for 5 consecutive days (m5 and s5, respectively), followed by high-dose (10 mg/kg) METH on day 6 (m5M and s5M, respectively). An accelerometer was used to evaluate the frequency of movement when rats were placed in a cage for 30 minutes. The expression of c-fos, a neuronal activity marker, in the striatum was analyzed using immunohistochemistry. Striatal protein expression of neuronal markers...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
In this study, there was no significant relationship between disease genotype for DISC1 gene and schizophrenia. By increasing the heterozygote genotype in the population, the probability of the disease will increase and mutant homozygote genotypes will also be visible.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
This article considers the inverse of the therapeutic landscape: the traumatic landscape that harms its inhabitants, proposing it as one way of understanding how addiction is related to place. I draw on research in health geography, medical anthropology, and critical psychology to develop a novel theorization of the relationship between place, trauma, and addiction. Drawing on eighteen months of ethnographic fieldwork with drug users exiting the prison system in Chicago, Illinois, the article considers the life histories of two men whose addictions to drugs and alcohol are profoundly related to place. Through close reading...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
Publication date: Available online 14 March 2019Source: The Lancet HIVAuthor(s): Evgeny Krupitsky, Elena Blokhina, Edwin Zvartau, Elena Verbitskaya, Dmitri Lioznov, Tatiana Yaroslavtseva, Vladimir Palatkin, Marina Vetrova, Natalia Bushara, Andrei Burakov, Dmitri Masalov, Olga Mamontova, Daniel Langleben, Sabrina Poole, Robert Gross, George WoodySummaryBackgroundUntreated opioid addiction in people with HIV is associated with poor HIV treatment outcomes. Slow-release, long-acting, implantable naltrexone might improve these outcomes. Here, we present results of a study aimed to test this hypothesis.MethodsWe did a 48 week do...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
This article reviews the current understanding of super-enhancer assembly and activation, the different mechanisms by which cancer cells acquire oncogenic super-enhancers and, finally, the potential of targeting super-enhancers as future therapeutics.
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
The evolution of VR hardware and software What’s the best VR will do VR, AR, MR or spatial computing? The potential of interactive immersive reality Challenges and obstacles in adoption How will immersive reality transform everyday life? What was the last time you met sci-fi? The dark side of technology Imagine that a doctor sits down in Starbucks, places some glasses on his head, instantly invokes five screens and starts doing his diagnostic work. Robert Scoble, virtual reality expert, and tech evangelist believes that will be possible in the coming years – sooner than we might think. He told us why his wi...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Great Thinkers AR augmented reality future HoloLens Innovation MR Oculus technology virtual virtual reality VR XR Source Type: blogs
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