Orthodontic appliances did not increase risk of dental caries and periodontal disease under preventive protocol.

CONCLUSIONS:: A dynamic change in microbial levels was identified. The decrease in the levels of complexes present was only possible due to the mechanical method of oral hygiene implemented in this sample. PMID: 30239218 [PubMed - as supplied by publisher]
Source: The Angle Orthodontist - Category: Dentistry Authors: Tags: Angle Orthod Source Type: research

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Publication date: June 2020Source: Enzyme and Microbial Technology, Volume 137Author(s): Sara Arana-Peña, Nathalia S. Rios, Carmen Mendez-Sanchez, Yuliya Lokha, Luciana R.B. Gonçalves, Roberto Fernández-LafuenteAbstractA strategy to obtain biocatalysts formed by three enzyme layers has been designed using lipases A and B from Candida antarctica (CALA and CALB), the lipases from Rhizomucor miehei (RML) and Thermomyces lanuginosus (TLL), and the artificial chimeric phospholipase Lecitase Ultra (LEU). The enzymes were initially immobilized via interfacial activation on octyl-agarose beads, treated with po...
Source: Enzyme and Microbial Technology - Category: Biotechnology Source Type: research
ConclusionOur results showed that JZ-1 protects against HSV-2 infection, and this beneficial effect may be mediated by inducing autophagy via inhibition of the PI3K/Akt/mTOR signaling axis.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: December 2020Source: Japanese Dental Science Review, Volume 56, Issue 1Author(s): Yumiko Kawashita, Sakiko Soutome, Masahiro Umeda, Toshiyuki SaitoSummaryRadiotherapy, often with concomitant chemotherapy, has a significant role in the management of head and neck cancer, however, radiotherapy induces adverse events include oral mucositis, hyposalivation, loss of taste, dental caries, osteoradionecrosis, and trismus, all of which have an impact on patients’ quality of life. Therefore, it is necessary to implement oral management strategies prior to the initiation of radiotherapy in patients with head ...
Source: Japanese Dental Science Review - Category: Dentistry Source Type: research
Publication date: Available online 19 February 2020Source: Journal of Evidence Based Dental PracticeAuthor(s): Alex Júnio Silva da Cruz, Johana Alejandra Moreno-Drada, Jacqueline Silva Santos, Mauro Henrique Nogueira Guimaraes de Abreu
Source: Journal of Evidence Based Dental Practice - Category: Dentistry Source Type: research
There is increasing evidence that members of the gut microbiota, especially Fusobacterium nucleatum (F. nucleatum), are associated with Crohn’s disease (CD), but the specific mechanism by which F. nucleatum promotes CD development is unclear. Here, we first examined the abundance of F. nucleatum and its effects on CD disease activity and explored whether F. nucleatum aggravated intestinal inflammation and promoted intestinal mucosal barrier damage in vitro and in vivo. Our data showed that F. nucleatum was enriched in 41.21% of CD tissues from patients and was correlated with the clinical course, clinical activity, a...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Candida albicans is the most common fungal pathogen and relies on the Hog1-MAPK pathway to resist osmotic stress posed by the environment or during host invasions. Here, we investigated the role of SPT20 in response to osmotic stress. Testing a C. albicans spt20Δ/Δ mutant, we found it was sensitive to osmotic stress. Using sequence alignment, we identified the conserved functional domains between CaSpt20 and ScSpt20. Reconstitution of the Spt20 function in a spt20Δ/CaSPT20 complemented strain found CaSPT20 can suppress the high sensitivity to hyperosmotic stressors, a cell wall stress agent, and antifunga...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In conclusion, the current work on KR-12 suggests that dimerization together with backbone cyclization is an effective strategy for improving both potency and stability of linear antimicrobial peptides.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Had a weird case a couple of weeks ago. My partner, who is an outstanding technical surgeon for implants (one of the best I have seen) had a stim follow up while he was on vacation. The wounds were dehiscing and the incisions looked odd (my partner has had only two infections over a 25 year career, so he is pretty damn good). I took her to the OR and removed the stim, packing the incisions open. Initial cultures were negative, but eventually grew candida. This patient was a diabetic with a... candida fungal infection with stimulator
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Authors: Sekita Y, Murakami K, Yumoto H, Hirao K, Amoh T, Fujiwara N, Hirota K, Fujii H, Matsuo T, Miyake Y, Kashiwada Y Abstract Dental biofilms that form in the oral cavity play a critical role in the pathogenesis of several infectious oral diseases, including dental caries, periodontal disease, and oral candidiasis. Houttuynia cordata (HC, Saururaceae) is a widely used traditional medicine, for both internal and external application. A decoction of dried HC leaves (dHC) has long been consumed as a health-promoting herbal tea in Japan. We have recently reported that a water solution of HC poultice ethanol extract...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Summary The development of dental caries and periodontal diseases result from distinct shifts in the microbiota of the tooth‐associated biofilm. This in vitro study aimed to investigate changes in biofilm composition and structure, during the shift from a ‘supragingival’ aerobic profile to a ‘subgingival’ anaerobic profile. Biofilms consisting of Actinomyces oris, Candida albicans, Fusobacterium nucleatum, Streptococcus oralis, Streptococcus mutans and Veillonella dispar were aerobically grown in saliva‐containing medium on hydroxyapatite disks. After 64 h, Campylobacter rectus, Prevot...
Source: Oral Microbiology and Immunology - Category: Microbiology Authors: Tags: Original Article Source Type: research
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