Effect of High-Dose, Short-Duration β-Alanine Supplementation on Circulating IL-10 Concentrations During Intense Military Training

This study examined the effect of β-alanine as a potential anti-inflammatory agent during intense military training. Twenty soldiers (20.1 ± 0.6 years) from an elite combat unit were randomly assigned to either a β-Alanine (BA) or placebo (PL) group. Soldiers were provided with 12 g·d−1 of either BA or PL for 7 days between 2 intensive periods of navigational training and restricted sleep. During the initial training period, soldiers navigated on average 27.8 km·d−1 with ∼50% of their body mass in their packs for 5 days. Soldiers returned to base and began a 7-day supplementation program before departing for an additional period of intense field training. During the second period of field training, soldiers navigated 10 km·d−1 for an additional 5 days, carrying similar loading as the initial week, performed tactical missions, and slept approximately 5 hours per day. Blood samples were obtained after the initial training period and after the second training period and analyzed for IL-10. Magnitude-based inferences that were used to provide inferences on the true effect BA may have had on IL-10 concentrations compared with PL, calculated from 90% confidence intervals. Data analysis indicated that changes in circulating IL-10 concentrations (mean difference 0.86 pg·ml−1) were possibly greater (57%) for BA than PL. Results of this study suggest that 1 week of high-dose BA ingestion may enhance the anti-infla...
Source: Journal of Strength and Conditioning Research - Category: Sports Medicine Tags: Research Note Source Type: research

Related Links:

We examined whether screen time was associated with cardiometabolic disease (CMD) risk factors in young adults. Ninety-five adults (19.9  ± 11.4 years) self-reported medical and health behavior history, screen time (television viewing, video games and computer games), and dietary intake. Waist circumference, blood pressure, fasting glucose and lipid levels, cardiorespiratory fitness (VO2peak), and body composition were measured. Total sedentary behavior and moderate-to-vigorous physical activity (MVPA) were measured by accelerometer. On average, leisure screen time (2.0  ± 1.6...
Source: Journal of Behavioral Medicine - Category: Psychiatry Source Type: research
Authors: Urban AE, CubaƂa WJ Abstract Eugeroics are a relatively new class of wakefulness-promoting agents. Thegroup includes adrafinil, modafinil and armodafinil. Modafinil is the most widely used and the best studied agent. Indications for the use of modafinil include the treatment of narcolepsy, shift-work sleep disorders and excessive daytime sleepiness associated with obstructive sleep apnea. Many studies show the utility of modafinil and armodafinil in the treatment of depression - both in monotherapy andas potentiation therapy if needed. Modafinil has proven to be effective in the treatment of residual symp...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Publication date: August 2020Source: Cancer Epidemiology, Volume 67Author(s): Jessica McNeil, Emily Heer, Romy F. Willemsen, Christine M. Friedenreich, Darren R. Brenner
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
At any given time, more than a third of Americans are on a specific diet, with weight loss as a leading reason. Most are going to be disappointed, because even when successful, lost weight is frequently regained within a few months. While most weight-loss diets can help you lose weight, they may be unsuccessful over the long run for a number of reasons. Some people don’t follow their diets carefully and don’t lose much weight even from the start. Others may go off the diet entirely after a while, because it’s too restrictive or the foods aren’t appealing. Some may engage in less physical activity as...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diet and Weight Loss Source Type: blogs
HOW TO live longer: The secret to long life expectancy is a healthy lifestyle, which includes eating a healthy, balanced diet, not smoking, limiting alcohol intake, getting plenty of sleep and regular exercise. But when it comes to exercise, which one is best?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The global novel coronavirus pandemic afflicting everyone is showing mixed signs of activity. In some countries it appears to be easing, while in others it appears to be experiencing a resurgence. It’s not at all clear when the pandemic will end, but it’s unlikely to do so before 2021. What has become increasingly clear is that the toll of the pandemic will impact more than the people who come down with COVID-19. The mental health impact of living with a pandemic is being mostly ignored — for now. But as the deaths continue to rise, we need to pay close attention to the cost of the pandemic’s reperc...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Grief and Loss Health-related Mental Health and Wellness Policy and Advocacy coronavirus COVID-19 Source Type: blogs
Conditions:   Stroke;   Sleep-disordered Breathing;   Sleep Apnea Syndromes;   Sleep Apnea, Obstructive;   Sleep Apnea, Central;   Fragmentation, Sleep Intervention:   Device: Treatment according to standard care recommandation Sponsor:   University Hospital, Grenoble Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Caffeine;   Sleep Deprivation;   Shift-Work Related Sleep Disturbance Intervention:   Dietary Supplement: Caffeine Sponsors:   University of Arizona;   Walter Reed Army Institute of Research (WRAIR) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Sleep Disturbance;   Aging Intervention:   Behavioral: Cross-sectional assessments to examine the relationship among sleep quality, functional/physical capacity, and cognitive performance. Sponsors:   University of Calgary;   The Brenda Strafford Foundation Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
HOW TO sleep: Getting to sleep during hot weather can prove an impossible task and temperatures are forecast to hit the mid-20s this week. So what can you do to ensure some decent shut-eye? A group of experts have offered four simple hacks.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
More News: Sleep Disorders | Sleep Medicine | Study | Training | Universities & Medical Training