Loss Of Prolyl-Hydroxylase 1 Protects Against Biliary Fibrosis Via Attenuated Activation Of Hepatic Stellate Cells

In this study, we demonstrate that loss of prolyl-hydroxylase 1 (PHD1-/-) attenuates the development of liver fibrosis in mice subjected to chronic bile duct injury, induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine.

Source: American Journal of Pathology - September 21, 2018 Category: Pathology Authors: Moritz J. Strowitzki, Johanna Kirchberg, Christopher Tuffs, Maximilian Schiedeck, Alina S. Ritter, Marvin Biller, Jonathan M. Harnoss, Felix Lasitschka, Thomas Schmidt, Praveen Radhakrishnan, Alexis Ulrich, Martin Schneider Tags: Regular Article Source Type: research