Abnormal cerebellum-DMN regions connectivity in unmedicated bipolar II disorder

Bipolar disorder (BD), a severe, chronic psychiatric disease, is a leading cause of disability, morbidity, and mortality from suicide, and is associated with several medical conditions, such as cardiovascular disease, diabetes mellitus, and neurovascular disease (Merikangas et al., 2007; Prieto et al., 2014). It is characterized by episodes of depression, mania (BD I), and hypomania (BD II) that seriously affect the social functioning and quality of life of patients (Dean et al., 2004; Merikangas et al., 2007).

Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Guanmao Chen, Lianping Zhao, Yanbin Jia, Shuming Zhong, Feng Chen, Xiaomei Luo, Shaojuan Qiu, Shunkai Lai, Zhangzhang Qi, Li Huang, Ying Wang Tags: Research paper Source Type: research