Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice [Microbial Immunity and Vaccines]

This study shows that adding RTX antigen to an appropriate dose of aP can enhance protection against B. pertussis challenge in mice.

http://iai.asm.org/cgi/content/short/86/10/e00857-17?rss=1

Source: Infection and Immunity - September 21, 2018 Category: Infectious Diseases Authors: Boehm, D. T., Hall, J. M., Wong, T. Y., DiVenere, A. M., Sen-Kilic, E., Bevere, J. R., Bradford, S. D., Blackwood, C. B., Elkins, C. M., DeRoos, K. A., Gray, M. C., Cooper, C. G., Varney, M. E., Maynard, J. A., Hewlett, E. L., Barbier, M., Damron, F. H. Tags: Microbial Immunity and Vaccines Source Type: research