MrpJ Directly Regulates Proteus mirabilis Virulence Factors, Including Fimbriae and Type VI Secretion, during Urinary Tract Infection [Bacterial Infections]

In conclusion, this study (i) establishes the direct gene regulon and an MrpJ consensus binding site and (ii) led to the discovery of new virulence genes in P. mirabilis UTI, which could be targeted for therapeutic intervention of CAUTI.

Source: Infection and Immunity - September 21, 2018 Category: Infectious Diseases Authors: Debnath, I., Stringer, A. M., Smith, S. N., Bae, E., Mobley, H. L. T., Wade, J. T., Pearson, M. M. Tags: Bacterial Infections Source Type: research